Valdenafil is a PDE-5 inhibitor used to treat erectile dysfunction (ED) in men. It relaxes the smooth muscles in the walls of blood vessels, increasing blood flow to certain areas of the body, including the penis.

People with erectile dysfunction have difficulty getting and maintaining an erection during sex. During sexual stimulation, a chemical known as nitric oxide is released into the penis. It is secreted by nerve endings and endothelial cells in the corpus cavernosum.

Nitric oxide is involved in the production of cyclic guanosine monophosphate (cGMP), which induces muscle relaxation and regulates vasodilation and contraction.

The PDE5 enzyme destroys cGMP and does not cause an erection. Vardenafil blocks the action of PDE5 so that it can properly produce cGMP. This ensures adequate blood flow to the penis. As more and more blood enters the penis, the pressure builds. This causes an erection.

This drug is sold as Levitra in doses of 10mg, 20mg, 40mg, 60mg, etc. Common versions of this drug include

• Vilitra 20
• Zhewitra 40
• Valif 20

For this drug to work properly, it must stimulate the person sexually. This drug does not provide orgasm and does not increase sexual activity. It is recommended to take 1 tablet within 24 hours. For most patients, a starting dose of 20 mg is recommended.

This drug is often used in patients with erectile dysfunction as a result of cardiovascular disease. The effect of this medicine lasts for 5 hours. For best results, take the drug on an empty stomach and 1 hour before sexual intercourse. Read all the instructions on the leaflet according to the prescribed dosage of your medicine. Dosage changes should only be made after receiving a prescription from a doctor.